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Practice sessionHEALTHCARE & MEDICAL EXAMSMEDICAL LICENSING

USMLE (United States Medical Licensing Examination) Practice Exam 03

Practice exam for USMLE (United States Medical Licensing Examination).

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Question 1 of 1000%
Time remaining180:00
Attempts allowedUnlimited
Difficulty mixE • M • H
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Question 1

EASY

A 62-year-old man with long-standing hypertension is started on a medication that blocks angiotensin II type 1 (AT1) receptors. Two weeks later, his blood pressure has improved. Which of the following changes is most likely to occur in the efferent arteriole of the glomerulus as a direct effect of this medication?

Angiotensin II preferentially constricts the efferent arteriole via AT1 receptors. Blocking AT1 receptors (eg, ARBs) decreases efferent arteriolar constriction, leading to efferent dilation and reduced intraglomerular pressure. Key distractors: Prostaglandins primarily dilate the afferent arteriole; angiotensin II does not act primarily on the afferent arteriole.

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